Course Objectives: Learn the importance of minimizing waste, saving power and doing organic synthesis according to the principles of green chemistry
Learning outcomes: At the end of the course, the learners should be able to:
Create awareness for reducing waste, minimizing energy consumption in organic synthesis.
Implement techniques of green synthesis in organic reactions
Green Chemistry Definition, need for Green chemistry, evolution of Green Chemistry, principles of Green Chemistry.
Classification of organic reactions under Green chemistry principles: a) Atom economic and non-toxic byproduct reactions: rearrangements, addition reaction, condensations, cascade strategies under catalysis, b) atom uneconomic reactions: substitutions, eliminations, Wittig reactions, degradation reactions
Green Strategies and techniques for Organic Synthesis: use of Microwave, Sonochemsitry, Ball mill technique, electrochemical reactions, photochemical reactions,
Catalysis: Principles of various catalysis techniques in terms of Green Organic Synthesis
i) Homogeneous, ii) Heterogeneous, iii) bio (enzyme) catalysis, iv) catalysis with non-toxic metals (Ca, Fe, Co, etc.), v) solid supported catalysis, vi) metal free/organocatalysis, vii) Visible light catalysis viii) phase transfer catalysis Alternative/Green Solvents for Organic Synthesis i) Water, ii) Ionic liquids, iii) Supercritical liquids (SCL), iv) Poly(ethylene glycol) (PEG), v) Fluorous biphasic Solvents
Comparison of greenness of solvents
Understanding the role/effect of these solvents on organic reactions
Solvent Free Organic Synthesis
Reactions at Room Temperature
Applications of the Green strategies in Organic Synthesis
Comparing various organic reactions under classical conditions and Green conditions.