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DR. MURALEEDHARAN, K. M.

DEPARTMENT OF CHEMISTRY

Professor

  • Email: mkm@iitm.ac.in
  • Phone: +91-44-2257-4233
  • Address: CYB 301, Department of Chemistry
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BIOGRAPHY

Muraleedharan K. M. hails from the Kannur Dt. of Kerala State. He did his Master’s degree in Chemistry studying at the School of Chemical Sciences, Mahatma Gandhi University during 1991 – 93. Subsequently he joined the research group of Professor Subramania Ranganathan at NIIST trivandrum for doctoral research which focused on the synthesis of models systems to understand molecular – assembly and dis – assembly, the key processes in every biological function. Following a brief stint at IICT Hyderabad (1999 – 2000), he moved to the research group of Professor Mitchell A. Avery at the Univesity of Mississippi, the USA for post – doctoral research where he was working on the development of broad – spectrum anti – infective agents. He joined the department of Chemistry at IIT Madras in 2006 as an Assistant Professor and since then, his group has been working on various projects under the broad umbrella of medicinal – and Bioorganic Chemistry.

 
  • 2001 – 2006, Post – doctoral Research Associate, Department of Medicinal Chemistry, University. of Mississippi, USA (in the research group of Prof. Mitchell A. Avery).
  • 1999 – Ph. D from NIIST Trivandrum (Supervisor, Prof. Subramania Ranganathan)
  • 1993 – M. Sc from School of Chemical Sciences, Mahatma Gandhi University, Kerala.
  • 1991 – B. Sc from Nirmalagiri College, Calicut University, Kerala.
  1. Muraleedharan K. M., Peroxide-based Anti-parasitic agents – Invited lecture during the national seminar on ‘Advances in Research and Innovations in Chemistry’, at PSGRK College for Women, Coimbatore during 27th-28th September 2007
  2. Muraleedharan K. M., ADMET in Drug Discovery – Seminar during Conference cum Workshop on Current Trends in Medicinal Chemistry April 2-4, 2009 at IIT Madras.
  3. Muraleedharan K. M., Spectro-analytical tools in Organic- and Bio-molecular Chemistry – Invited lecture during the UGC Sponsored national seminar on ‘Hot trends in Analytical Spectroscopy’, at MAMO College, Calicut University, during 14th-15th October 2009
  4. Muraleedharan K. M. Sensing the ‘Pulses’ of Chemical Reactions: Synthesis of Multi-Functionalized Organic Frame-works with Potential Application in Medicine – Invited lecture during the UGC Sponsored national seminar on ‘Emerging trends in Chemical sciences’ at Payyanur College, Kannur University, during 22th-24th October 2009.
  5. Muraleedharan K. M. ‘Medicinal Chemistry’ Lecture to teachers from different universities, as part of a refresher course organized by the Academic staff college, Kannur University on 18th Jan 2011.
  6. Muraleedharan K. M., ‘Co-operative rotamer preferences during folding, and chemical environment-dependant aggregation of a,b 2,3– hybrid peptides’ – Invited lecture during National Conference on Chemistry Education and Research Frontiers’ on the occasion of celebrating the “International Year of Chemistry 2011” at IGNOU on October 13, 2011.
  7. Muraleedharan K. M., ‘Anti-malarial peroxides: A bird’s eye view’ during one day international symposium on “Anti-malarials: Current Approaches and New Directions” organized jointly by Open Source Drug Discovery malaria (OSDDm), OSDD-Chemistry Outreach Program (OSDD Chem) and Medicines for Malaria Venture (MMV) at CSIR-Central Drug Research Institute, Lucknow on 16th November, 2011.
  8. Muraleedharan K. M. ‘Anti-malarial Peroxides: Current Status and Future Prospects’ – Invited lecture during CSIR NIIST–ACT National Workshop on frontiers in organic synthesis and Drug discovery on 1st March, 2012 at NIIST Trivandrum.
  9. Muraleedharan K. M. ‘Anti-cancer drug candidates based on redox-active heterocyclic scaffolds – Invited talk during international symposium on Chemistry and Chemical Biology of Natural Products during August 2-4, 2012 at CSIR-IICT at Hyderabad.
  10. Muraleedharan K. M. and D. Balamurugan. ‘Co-operative Rotamer Preferences During Folding and Environment-Dependant Aggregation in a,b2,3– Hybrid peptides – invited talk during XV NOST (National Organic Symposium Trust) conference  during October 10-13, 2012 at Jaypee palace Agra.
  11. Muraleedharan K. M. ‘Folding and Aggregation Profiles of α,β 2,3– Hybrid Peptides’ Science Academies Lecture Workshop on ‘Recent Advances in Materials Science, June 24-25, 2013 at Payyanur College Kerala.
  12. Muraleedharan K. M. ‘folding preferences and self-assembly profiles of β2,3-peptides’, National conference on green processes and nano-materials (NCGPNM 2014) at Hindustan Institute of Technology and Science, Padur, Chennai 603 103, during 8-9th January 2014.
  13. Muraleedharan K. M. ‘Chemical Environment-dependant Folding and Aggregation in b2,3-Peptides’, National seminar on Current Trends in Chemistry (Ctric), department of applied Chemistry, Cochin University of Science and Technology 17-18th January, 2014,.
  14. Muraleedharan K. M. ‘Redox modulation of cancer cell proliferation’, National Seminar on Recent trends in Chemical Sciences organized by the department of Chemistry, Nirmalagiri College on 24-3-2014.
  15. Muraleedharan K. M. National Conference on Computer Aided Drug Design and Development Organized by Srinivasa Ramanujan Institute For Basic Science (SRIBS) Pampady, Kottayam (A Capacity Building Initiative of KSCSTE) In association with Indian Institute of Information Technology and Management – Kerala at Technopark, Trivandrum on 27th March 2014.
  16. Muraleedharan K. M. ‘Supramolecular Foldamer Assembly – Design Principles and Potential Applications’, Colloquium on ‘Recent Trends in Organic and Bioorganic Chemistry’, Organized by Srinivasa Ramanujan Institute for Basic Science (SRIBS) at Kottayam on 20th July 2014.
  17. K M Muraleedharan, ‘Repositioning of Quinolones to New Therapeutic Areas: Pros and Cons’, Indo-French Conference/workshop titled ‘New Trends in Chemistry and Chemical Biology with Special Focus on CNS Disorders’ organized by IICT Hyderabad at Pondicherry on 10th, 2014.
  18. Muraleedharan K. M., ‘A Closer Look at Helix Formation and Unwinding in a,b2,3-Peptides’, 13th Eurasia Conference on Chemical Sciences, J. N. Tata Auditorium, Indian Institute of Science, Bangalore. 14-18, 2014.
  19. Muraleedharan K. M., ‘Specific and non-specific cellular responses from redox-active heterocycles: Dihydroquinolines as promising scaffolds for ‘multi-targeting’, MedChem India 2015 Conference organized by Select Biosciences India at Hotel Radisson Hitec City, Hyderabad, India during 10-11 September 2015.
  20. Muraleedharan K. M., ‘Dihydroquinolines as redox modulators with anti-proliferative and anti-bacterial properties’, Drug Discovery & Development: Global Scenario-Indian Perspective” Conference held at NIPER-Hyderabad during 20th and 21st November, 2015 (Supported by the Dept. of Pharmaceuticals, Ministry of Chemicals and Fertilizers.
  21. Muraleedharan K. M., ‘Non-Covalent Interactions in Material Science and Medicine’, UGC sponsored National Seminar on “Organic synthesis” hosted by St’ Josephs College, Irinjalakkuda, Thrissur, Kerala, 28th-29th, Jan 2016.
  22. Muraleedharan K. M., ‘Control of molecular conformation and properties through non-covalent interactions’, KSCSTE sponsored two-day national seminar “Green Strategies & Technologies” on February 18-19, 2016, at Post Graduate & Research Department of Chemistry, St. Joseph’s College, Devagiri, Calicut.
  23. Muraleedharan K. M., ‘Chemical Approaches to ADMET Modulation in Drug Development’- talk given on 14-03-17; Two-day Lecture Workshop on “Organic Chemistry – From bench to Industry” organized at NMKRV College for Women, Bengalure-560011 during 14-15th March, 2017 with the support of Indian Academy of Sciences, Bangalore, Indian National Science Academy, New Delhi and the National Academy of Sciences, Allahabad .
  24. Muraleedharan K. M., Hydroxylated Oxanorbornane skeleton as head group in lipids, and design of New Drug Delivery Systems; One day workshop “Innovative Lead Optimization and Candidate Selection” organized at Stella Maris College, Chennai on October 13th, 2017.
  25. Muraleedharan K. M., Drug Discovery – Challenges and Strategies, National Seminar on ‘Medicinal and Computational Chemistry 2017, in the department of Chemistry at Govt. College Madappally, Vadakara on 24th Nov, 2017, sponsored by Directorate of Collegiate Education, Govt. of Kerala.
  26. Kottayam ramanujan
  27. St josephs iringalakkuda
  28. Varanasi talk
  29. CiHS 2018
  30. Tamil Nadu science forum
  31. Brennen college
  32. Malabar Christian college
  33. Christ College