Bruker AVANCE™ 400

The fundamentally superior precision and stability of fully digital signal generation and processing has been introduced and established by the precedent-setting series of AVANCE™ NMR spectrometers. With its digital advantage, the Bruker AVANCE™ series sets revolutionary standards for performance, long-term reliability and ease-of-use, whether for routine applications or the most demanding research.
The modular AVANCE™ architecture makes extensive use of high-performance RISC-based digital signal processors in the lock channel, timing control unit, gradient generator, data  acquisition unit, and other key areas of the system. The result is increased sensitivity, higher dynamic range, cleaner spectra, flat baselines and unprecedented long-term stability.

A full range of NMR capabilities is available for the AVANCE™, including Micro-Imaging, CPMAS, MQ-MAS, wide-line NMR of solids and CRAMPS. A variety of options for gradient-assisted spectroscopy (GRASP) are also available, utilizing one or  three field gradients. Gradient shapes are calculated on-the-fly providing the equivalent of an infinite wave form memory. Systems may be equipped with a sample changer for  completely automated analysis of up to 120 liquid samples or  30 CPMAS solid samples.
The fantastic performance of the AVANCE™ in high resolution (HR) and particularly in Solids Spectroscopy could only be reached with the continuing development applying latest RF and digital technologies. This also allowed for the unprecedented compactness of the Acquisition System (AQS) module, which houses the complete acquisition electronics, from frequency
generation to receiver and digitization. Through its advanced modular design the AVANCE™ can be optimally configured for any modern application: from classical analytical work to the most demanding structural  proteomics; from high-throughput screening to high-power solids NMR to micro imaging. Depending on the required techniques and the laboratory space available, the AVANCE™ can be delivered in a variety of configurations, ranging from a
minimum-footprint microbay system (for applications utilizing one, two, or three frequency channels) up to a three cabinet instrument fully equipped for high power solids NMR with four or more channels.

Key Features
   AQS Channel Concept
   Digital Lock
   Power Amplifiers
  Modular Concept
  Digital Signal Routing
  Gradient Spectroscopy
  Over sampling & Digital Filtering
  Gradient Amplifiers
  Variable Temperature Unit









© 2012, All rights reserved, Dept. of Chemistry, IITM