• Publication
  • PATENTS
  1. Stereoselective total synthesis of Oxylipin from open chain gluco-configured building block, Borkar, S. R.; Aidhen, I.S. Carbohydrate Research, 2017, 443-444, 23-28.

  2. α,α-Diarylethylene Glycols as Valuable Precursor for Synthesis of 1,1-Diarylethenes and α,α-Diaryl Acetaldehydes, Tiwari, P. K.; Sivaraman, B.; Aidhen, I. S. Eur. J. Org. Chem. 2017, 3594-3605.

  3. Valuable Building Block for the Synthesis of Lunularic Acid, Hydrangeic Acid and Their Analogues. Mukkamala, R.; Hossian, A.; Aidhen, I. S. Nat. Prod. Res., 2017, 31, 1085-1090.

  4. Synthesis of Threo- and Erythro- Configured Trihydroxy Open Chain Lipophilic Ketones as Possible Anti-Micobacterial Agents. Borkar, S. R.; Bokolia, N.;  Aidhen, I. S.; Khan, I. A. Tetrahedron Asymmetry, 2017, 186-195

  5. Convenient Synthesis of 3-Glycosylated Isocoumarins. Sudarshan, K.; Aidhen, I.S. Eur. J. Org. Chem., 2017, 34-38

  6. Facile Formation of 5-Acylated-2-hydroxymethyl–furans from Open Chain D-Glucosyl-Alkyl/ Aryl Ketones. Borkar, S. R.; Aidhen, I. S. Chemistry select, 2016, 1, 6004-6007.

  7. Metal-free bipolar/octupolar organic dyes for DSSC application: A combined experimental and theoretical approach. Mandal, S.; Kushwaha, S.; Mukkamala, R.; Siripina, V. K.; Aidhen, I. S.; Rajakumar, B.; Kothandaraman, R. Org. Electron. 2016, 36, 177-184.

  8. A Weinreb Amide Based Building Block for Convenient Access to β,β-Diarylacroleins: Synthesis of 3-Arylindanones. Tiwari, P. K.; Aidhen, I. S. Eur. J. Org. Chem., 2016, 2637-2646.

  9. Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3- aryl isocoumarins. Ramanan, M.; Sinha, S.; Sudarshan, K.; Aidhen, I.S.; Doble, M. Eur. J. Med. Chem., 2016124,  428-434.

  10. Enhanced two photon absorption cross section and optical nonlinearity of a quasi-octupolar molecule. Namboodiri, C. K. R.; Bongu, S. R.; Bisht, P. B.; Mukkamala, R.; Chandra, B.; Aidhen, I. S.; Kelly, T. J.; Costello, J. T. J. Photochem. Photobiol., A 2016, 314, 60-65.

  11. New building blocks for convenient access to positional isomers of FTY720 and analogues. Borkar, S. R.; Bej, R.; Aidhen, I. S. ARKIVOC 2016, 2, 148-161.

  12. A Common Building Block for the Syntheses of Amorfrutin and Cajaninstilbene Acid Libraries toward Efficient Binding with Peroxisome Proliferator-Activated Receptors. Aidhen, I. S.; Mukkamala, R.; Weidner, C.; Sauer, S. Org. Lett., 2015, 17, 194-197.

  13. Some interesting 1H NMR features of ortho substituted N-methoxy-N-methyl benzamides. Harikrishna, K.; Sivaraman, B.; Ananya, R.; Aidhen, I. S. Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem., 2015, 54B(1), 77-83.

  14. Synthesis of 3-Arylisocoumarins by Using Acyl Anion Chemistry and Synthesis of Thunberginol A and Cajanolactone A. Sudarshan, K.; Manna, M. K.; Aidhen, I. S. Eur. J. Org. Chem., 2015, 1797-1803.

  15. A molecular level understanding of interaction between FTY720 (Fingolimod hydrochloride) and DMPC multilamellar vesicles. Swain, J.; Borkar, S. R.; Aidhen, I. S.; Mishra, A. K. RSC Adv., 2014, 4, 17347-17353.

  16. Acyl-anion chemistry for the synthesis of C-aryl glycosides: synthetic efforts towards C-aryl septanosides. Harikrishna, K.; Tiwari, P. K.; Aidhen, I. S. Trends Carbohydr. Res., 2014, 6, 37-46.

  17. Iodine-Promoted Oxidative Conversion of o-Vinyl Diaryl Ketones into o-Acetyl Diaryl Ketones, Synthesis of 1-Methyl-4-arylphthalazines as Analogues of Podophyllotoxin. Harikrishna, K.; Mukkamala, R.; Hinkelmann, B.; Sasse, F.; Aidhen, I. S. Eur. J. Org. Chem., 2014, 1066-1075.

  18. A Defunctionalization Concept for the Convenient Synthesis of Bis(5-arylfuran-2-yl)methane Scaffolds. Tiwari, P. K.; Mukhopadhyay, T.; Aidhen, I. S. Eur. J. Org. Chem., 2013, 8083-8086.

  19. Convenient synthesis of ophiocerin C. Borkar, S. R.; Manjunath, B. N.; Aidhen, I. S. Trends Carbohydr. Res., 2013, 5, 34-38.

  20. Study of aqueous phase aggregation of FTY720 (fingolimod hydrochloride) and its effect on DMPC liposomes using fluorescent molecular probes.
    Swain, J.; Mohapatra, M.; Borkar, S. R.; Aidhen, I. S.; Mishra, A. K. Phys. Chem. Chem. Phys., 2013, 15, 17962-17970.

  21. Study of the Chemoselectivity of Grignard Reagent Addition to Substrates Containing Both Nitrile and Weinreb Amide Functionalities.
    Harikrishna, K.; Ananya, R.; Aidhen, I. S. Eur. J. Org. Chem., 2013, 4918-4932.

  22. Weinreb amide based building block for convenient access to vinyl ketones. Tiwari, P. K.; Aidhen, I. S. Synlett 2013, 1777-1780.

  23. Synthesis of (+)-centrolobine and its Analogues Based on Acyl Anion Chemistry, Sudarshan, K.; Aidhen, I. S. Eur. J. Org. Chem., 2013, 2298-2302.

     

  24. Convenient Access to Acyl-substituted Bis-styrylbenzenes using Building Blocks Based on Julia olefination &Weinreb-amide chemistry, Mukkamala, R.; Senthilmurugan, A.; Aidhen, I. S. Eur. J. Org. Chem., 2013, 2216-2229.

  25. Solvatochromism, multiphoton fluorescence, and resonance energy transfer in a new octupolar dye-pair. Namboodiri, R. C.; Bisht, P. B.; Mukkamala, R.; Chandra, B.; Aidhen, I. S. Chemical Physics2013, 415, 190-195.

     

  26. Attempted synthesis of ophiocerin A using D-gulonic acid-δ-lactone. Manjunath, B. N.; Aidhen, I. S. Arkivoc2013, 2, 100-111.

     

  27. Convenient synthesis of D- and L-xylo-1,2,3,4-alkane tetrols from a D-gluco-configured common building block. Borkar, S. R.; Manjunath, B. N.; Sivaraman, B. Aidhen, I.S. Carbohydrate Research2012, 358, 23 – 30.

  28. Convenient strategies for the synthesis of 1,4-phenylene spaced sugars. Senthilmurugan, A.; Aidhen, I.S. Carbohydrate Research2012, 347, 55 – 63.

     

  29. Weinreb Amide Based Building Blocks for the synthesis of a- and b-Organylseleno Aryl Ketones, Sivaraman. B.;  Aidhen, I. S, Synlett 2011, 1533-36.

  30. A new fluorescent probe with stimulated emission and multiphoton absorption properties. Akbar Ali, S.; Bisht, P.B.; Senthilmurugan, A.; Aidhen, I.S.  Chemical Physics2011382, 68-73.

  31. Weinreb Amide Based Building Blocks for Convenient Access to 1,1-Diarylethenes and Isocombretastatin Analogues., Sivaraman, B.; Harikrishna, K.; Aidhen, I. S. Tetrahedron Letters201152, 2683-2686.

  32. Novel Synthetic Strategy for biphenyl-spaced sugars towards heparinoid mimetics. Trends in Carbohydrate Research. 20113, 33-43.

  33. Weinreb Amide Based Building Blocks for Convenient Access to Novel Analogues of Phenstatin. Sivaraman, B.; Aidhen, I. S. Eur. J. Org. Chem.2010, 4991-5003.

  34. Synthesis of (+)-Varitriol Analogues via Novel and Versatile Building Blocks Based on Julia olefination. Senthilmurugan, A.; Aidhen, I. S. Eur. J. Org. Chem.,2010, 555-564.

  35. Synthesis of (+)-Varitriol Analogues via Novel and Versatile Building Blocks Based on Julia olefination. Senthilmurugan, A.; Aidhen, I. S. Eur. J. Org. Chem.,2010, 555-564.

     

  36. 2-O-Benzylation in D-Gluconamide derivative under basic conditions with complete retention of stereo-integrity: Convenient access to 2-O-benzyl-3, 4:5, 6-di-O-isopropylidene-D-glucitol and other differently protected D-glucitol derivatives. Manjunath, B. N.; Harikrishna, K.; Verghese, B.; Aidhen, I. S. J. Carbohydrate Chem. 200928, 264-277.

     

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  37. Weinreb Amide Based Building blocks for Convenient Access to Various Synthetic Targets. Sivaraman, B.; Manjunath, B. N.; Senthilmurugan, A.; Harikrishna, K.; Aidhen, I. S. Ind. J. Chem., 200948B, 1749-1756.

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  38. A new distyrylbenzene derivative with Weinreb amide functionality: An efficient laser dye and nonlinear optical material, Kalanoor, B. S.; Bisht, P. B.; Senthilmurugan, A.; Aidhen, I. S. J. Luminescence2009129, 1094-1098.

  39. Review: The Growing Synthetic Utility of the Weinreb Amide, Sivaraman, B.; Aidhen, I. S. Synthesis2008, 3707- 3738

     

  40. Synthesis of a stable, storable and differentially protected acyclic precursor of D-amicetose and its conversion to 4-O-benzyl-protected-D-amicetose Aidhen, I. S.; Satyamurthi, N. Ind. J. Chem., Sec B2008, 47B 1851-1857

  41. Weinreb Amide based new Synthetic equivalents for convenient access to Immunosuppressive Agent FTY720 and analogues. Sivaraman. B.; Annamalai, S.; Aidhen, I. S, Synlett 2007, 2841-2846.

  42. Synthetic equivalents based on Weinreb amide functionality for convenient access to mono-protected a-diketones. Sivaraman. B.; Aidhen, I. S, Synlett 2007, 959-963

  43. Obtainment of an unusual product from attempted methylenation of 1,2:3,4:5,6 -Tri-O-isopropylidene-D-gluconolactone using benzothiazol-2-ylmethylsulfone under Julia conditions Manjunath. B. N., Varghese. B., Aidhen, I. S. J. Carbohydr. Chem2007, 26, 17-25.

     

  44. New reagent for convenient access to the ab-unsaturated N-methoxy-N-methyl-amide functionality by a synthesis based on the Julia olefination protocol. Manjunath, B. N.; Neeraj, P. S.; Aidhen, I. S. Eur. J. Org. Chem. 2006, 2851-2855.

     

  45. Propargyl bromide as an excellent a -Bromoacetone equivalent: Convenient and New route to a-aroylacetones, Mahalingam, S. M.; Aidhen, I. S. J. Org. Chem2006, 71, 349-351.

  46. An Overview of various approaches for the synthesis of 1, 2-Dideoxy-b-Aryl or heteroaryl-D-ribo-furanose framework. Mahalingam, S. M.; Manjunath, B. N.; Aidhen, I. S. Proc. Ind. Nat. Sci. Acad. 2005 71A, 267-282

     

  47. Efficient and Rapid Regioselective Deprotection of Isopropylidene Ketals. Mahalingam, S. M.; Aidhen, I. S. Z. Naturforsch. 2005, 60b, 962-966.

     

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  48. Unambiguous assignment of the stereochemistry at the anomeric carbon in methyl-a-D-C-aryl-glucopyranoside derivative: A representative of products from our new strategy for 2-deoxy-C-aryl-glucopyranosides. Mahalingam, S. M.; Vijayasaradhi, S.; Aidhen, I. S. J. Carbohydr. Chem. 2005 24, 321-325.

  49. Convenient Enantiopure Synthesis of (2S,3R)-2-O-benzyl-3,4-O-isopropylidene-D-Erythritol from D-(+)-Glucono-d-lactone: A Potential C4 Chiral Building block. Vijayasaradhi, S.; Manjunath B. N.; Aidhen, I. S. Synthesis2005, 2267.

  50. Simple and highly convenient two step practical procedure for the synthesis of optically pure Methyl-D-erythro-2, 3 dihydroxybutanoate. Sathyamurthi, N.; Mahalingam, S. M.; Aidhen, I. S. Adv. Synth. Catal. 2005, 347, 715 – 717.

     

  51. Towards the Synthesis of Vigabatrin Using Glycal Chemistry. Boga, S. B.; Singh, J.; Aidhen, I. S. Molecules, 2005 10, 871–883

  52. Attachment of Arabino Configured 3, 4, 5, 6-Tetrahydroxy Hexyl Chain to an Aromatic Ring: Efforts toward 1, 4-Phenylene Spaced Sugars. Mahalingam S M.; Aidhen, I.S. Trends in Carbohydrate Chemistry 2004, 9, 71-74.

  53. An umpolung Strategy for the Synthesis of 2-Deoxy-C-aryl ribofuranosides. Vijayasaradhi, S.; Aidhen, I.S. Trends in Carbohydrate Chemistry 2004, 9, 65-70.

  54. Consequences of rigidity and conformational locking in a 4, 4-dimethyl-1, 3-dioxolane ring system during protection of internal diol. Vijayasaradhi, S.; Aidhen, I.S.; Varghese B., Carbohydrate Research 2003 338(24) 2899

  55. Umpolung Strategy for the Synthesis of 2-Deoxy-C-aryl glycosides: A serendipitous efficient route for C-Furanoside Analogues. Vijayasaradhi, S.; Aidhen, I.S.Organic Letters2002, 4, 1739-1742.

     

  56. Simple Synthetic Equivalents for the b-(N, N-disubstituted)ethylamino Acyl Cation Synthon and their Applications. V. Selvamurugan, Aidhen I.S, Synthesis,2001, 15, 2239-2246

     

  57. N-Methoxy-N-methyl 3-Bromopropionamide: A New Three Carbon Homologating Agent for the Synthesis of Unsymmetrical 1, 4-Diketones. V. Selvamurugan, Aidhen I.S. Tetrahedron2001, 57, 6065-6069.

  58. A Novel and Convenient Approach to 5-Aryltetrahydro-2-furanols. V. Selvamurugan, Aidhen I.S. J.Chem. Res (S)2000, 590-592.

     

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  59. Review: The Growing Synthetic Utility of Weinreb’s Amide. Singh, J.; Satyamurthi, N.; Aidhen, I.S. J. Prakt. Chem2000, 342-347.

     

  60. Synthesis and Application of N-Methoxy-N-Methyl-2-Phenylsulfonyl Acetamide as a two Carbon Homologating Agent. Satyamurthi, N.; Singh, J.; Aidhen, I.S.Synthesis2000, 3, 375-382

  61. An Efficient Selective Hydrolysis of Terminal Isopropylidene Acetal Protection by Zn(NO3)2 6H2O in Acetonitrile. Vijayasaradhi, S; Singh, J.; Aidhen, I.S.Synlett2000, 110-112.

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  62. An Efficient Synthesis of 4,5-O-Isopropylidene Protected L-(-)-Rhodinose, Satyamurthi, N.; Aidhen, I.S., Carbohydrate Letter1999, 3(5), 355-360.

     

  63. Convenient Conversion of Acid to Weinreb’s amide, Raghuram, T.; Vijaysaradhi, S.; Aidhen, I.S.; Singh, J. Syn. Commun1999, 29, 3215-3219.

     

  64. Palladium-Catalyzed Coupling of Stannyl Allenes with Aryl iodides, Aidhen I.S.; R.Braslau, Synthetic Communications, 1994, 24(6), 789-797.

     

  65. A Novel and Versatile Synthesis of 1-Aryl-benzocyclobutenols and 1-Aryl-benzocyclobutenes, Aidhen I.S. Narasimhan N S. Indian J Chem1993 32B, 234-238.

     

  66. Intramolecular Arylation of a Soft Carbon Centre Using Mn(III) Acetate: Studies toward Spirostructure of Fredericamycin-A. Aidhen I.S. Narasimhan N.S.,Indian J Chem. 1993, 32B, 222-228.

     

  67. A Formal Synthesis of Steganone, Aidhen I.S.; Narasimhan N.S., Indian J Chem. 1993, 32B,211-221.

     

  68. A Novel Synthesis of Benzocyclobutenones, Aidhen I.S.; Ahuja J.R, Tetrahedron Letters, 1992, 33, 5431-5432.

     

  69. A Novel and Versatile Synthesis of 1-Aryl-benzocyclobutenols and 1-Aryl-benzocyclobutenes, Narasimhan N.S.; Aidhen I.S. Tetrahedron Letters, 1991, 32, 2171-2172.

     

  70. Radical Mediated Reactions in Organic Synthesis, Narasimhan N.S.; Aidhen I.S.; Sunder N.M. J. Ind Chem Soc1989, 66, 703-709.

     

  71. Acyl Anion Equivalents in Synthesis of Anibine, Dhavale D.D.; Aidhen I.S.; Shafique M.; J. Org.Chem1989, 54, 3985-3987.

     

  72. Intramolecular Arylation of a Soft Carbon Centre or Enolate Using Mn(III) Acetate: Studies toward Spirostructures of Fredericamycin A, Narasimhan N S.; Aidhen I.S. Tetrahedron Letters 1989, 30, 5323-5324.

     

  73. Radical Mediated Intramolecular Arylation Using Tributyltinhydride/AIBN: A Formal Synthesis of Steganone Narasimhan N.S; Aidhen I.S. Tetrahedron Letters1988, 29, 2987-2988.

     

  1. Synthesis of amorfrutin and cajaninstilbene and their analogs from a common building block. Aidhen, I. S.; Mukkamala, R.; Indian Pat. Appl. 2015, IN 2013CH05457 A 20150529,

  2. Aidhen, I. S.; P. Bisht. A new dye for applications in dye laser and non-linear optics and as fluorescence life standard. Indian Patent application: 2643/CHE/October 2008.

  3. Vijayasaradhi, S.; Aidhen, I.S., A process for the efficient synthesis of (2S, 3R)-2-O-Benzyl-3,4-O-Isopropylidene-D-Erythritol, Indian Patent. Patent Application No: 543/MAS/2002 [Granted, Jan- 2007]

  4. Aidhen I.S. A process for the synthesis of Alkyl (S)-4-bromo-3-hydroxy-butanoate, US Patent: Application no: 0399NF2003 from Intellectual Property Rights division of CSIR, New Delhi.