• Recent Publications
  • Ph.D. and Postdoc
  • Patents
  • Research Highlights (IITM)
  • Highlights (PhD & Postdoc)
  1. Lewis basicity of water for a selective monodehalogenation of a,a-dihaloketones to a-haloketones and mechanistic study. Santhu Sadhukhan and Beeraiah Baire, Advanced Synthesis and Catalysis, 2017, in press, Link.

    SS-ASC

  2. Mechanistic Duality in Tertiary Amine Additions to Thermally Generated (HDDA) Benzynes. Sean P. Ross, Beeraiah Baire and Thomas R. Hoye. Org. Lett. 2017, ASAP, Link.

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  3. An Expeditious Approach to α,α-Dihalo-α′-acetoxyketones from Propargylic acetates. Santu Sadhukhan and Beeriaah Baire, Chemistry Select, 2017, 2, 8500-8503. Link

    slct201701398-toc-0001

  4. A Coherent study on the Z-enoate assisted Meyer-Schuster rearrangement. Prabhakararao Tharra and Beeraiah Baire, Organic & Biomolecular Chemistry, 2017,15, 5579-5584. link

    TPR OBC

  5. Carbonyl Directed, Regioselective Hydration of Alkynes under Ag-Catalysis. Jampani Santhi and Beeraiah Baire*, Chem. Select. 2017, 2, 4338-4332. Link

    SJ Chemselect

  6. Formal Total Synthesis of Selaginpulvilin D. Bhavani Shankar Chinta and Beeraiah Baire*, Org. Biomol. Chem., 2017, 15, 5908-5911link

    BS OBC

    A Cover Page graphic has also been accepted for this paper.

    BS-OBC Cover Page Graphic

  7. Ag(I) Catalyzed Cascade Approach to 2-(a-Hydroxyacyl)pyrroles. Soniya Gandhi and Beeraiah Baire. Chem. Select., 2017, 2, 3964-3968. link

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  8. First Synthesis of [5-5-6-6] Tetracyclic Framework of Spiropreussione B. Bhavani Shankar Chinta and Beeraiah Baire. Eur. J. Org. Chem., 2017, Accepted. link (Invited article)
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  9. On the Distribution of Linear vs. Angular Naphthalenes in Aromatic Tetradehydro Diels-Alder Reaction: Effect of Linker Structure and Steric bulk. Bhavani Shankar Chinta and Beeraiah Baire. Eur. J. Org. Chem., 2017, 3381–3385. link
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  10. Unconventional Reactivity of (z-enoate)Propargylic Alcohols in presence of Acids. Prabhakararao Tharra and Beeraiah Baire, Chemistry A European Journal, 2017, 23, 2014–2017. link

    TPR CAEJ

  11. Ag(I)-Catalyzed Cyclizative Hydration of Alkynes and Propargylic Alcohols. A Mild Approach to 2-Acylfuran Derivatives. Soniya Gandhi, Prabhakararao Tharra and Beeraiah Baire, Chemistry Select, 2017, 2, 1058. linkSG Chemselect

  12. Regioselective, Cascade [3+2] Annulation of b-Naphthols (Resorcinols) with Z-enoate Propargylic alcohols: A Novel entry into Complex Naphtho(benzo)furans. Prabhakararao Tharra and Beeraiah Baire, Chem. Comm.201652, 14290-14293. link.

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  13. Reactivity of indole-3-alkoxides in the absence of acids: Rapid synthesis of homo-bisindolylmethanes. Bhavani Shankar Chinta and Beeraiah Baire, Tetrahedron, 2016link

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  14. The dehydro Diels-Alder (DDA) reaction based approach to isofuranonaphthalenone, nodulones A-C and xestolactone A. Bhavani Shankar Chinta, Akshay Siraswar and Beeraiah Baire, Tetrahedron, 2016link (Invited Article)

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  15. Catalyst Free, Three-component Approach for Unsymmetrical Triarylmethanes (TRAMs). Bhavani Shankar Chinta and Beeraiah Baire, Tetrahedton Letters2016link

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  16. NIS promoted rapid access to indeno[1,2-c]pyrroles via [3+2] annulation of enamine-alkynes. Jampani Santhi and Beeraiah Baire, Adv. Synth. Catal. 2016. 358, 3817. link.

    SJ ASC

  17. The Z-enoate, Assisted Meyer-Schuster Rearrangement Cascade: Unconventiona Synthesis of a-arylenone esters. Prabhakararao Tharra, and Beeraiah Baire, Chem Commun., 2016, 52, 12147-12150. link Back cover page for this article got accepted

    TPR CC

    for website.giff

  18. A Systematic Study on Cadiot–Chodkiewicz Cross Coupling Reaction for Selective and Efficient Synthesis of hetero-diynes. Bhavani Shankar Chinta and Beeraiah Baire*, RSC Advances, 2016, 6, 54449-54455. link

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  19. Competition between classical and hexadehydro Diels-Alder (HDDA) reactions of HDDA triynes with furan. Quang L Nguyen, Beeraiah Baire and Thomas R Hoye, Tetrahedron Letters 2015, 56, 3265. link

    1-s2.0-S0040403914021078-fx1

  20. Rates of Hexadehydro Diels–Alder (HDDA) cyclizations: Impact of the Linker Structure. Brian P Woods, Beeraiah  Baire, and Thomas R Hoye, Organic letters, 2014, 16, 4578. link

    ol-2014-02131r_0008

  21. Mild Approach to 2-Acylfurans via Intercepted Meyer–Schuster Rearrangement of 6-Hydroxyhex-2-en-4-ynals.  Prabhakararao Tharra and Beeraiah Baire, J. Org. Chem., 2015, 80 (16), pp 8314-8328. link

    jo-2015-01420g_0013

  22. Stereoselective, Cascade Synthesis of trans-Enynones through Coupling-Isomerization Reaction Bhavani Shankar Chinta and Beeraiah Baire, J. Org. Chem., 2015, 80 (20), 10208–10217. link

    jo-2015-01780r_0013

  1. Thomas R. Hoye, Beeraiah Baire, Dawen Niu, Patrick H. Willoughby and Brian P. Woods, The hexadehydro-Diels–Alder reaction. Nature, 2012, 490, 208.

  2. Dawen Niu, Patrick H. Willoughby, Brian P. Woods, Beeraiah Baire and Thomas R. Hoye, Alkane desaturation via concerted dihydrogen transfer to benzyne.  Nature, 2013, 501, 531.

  3. Beeraiah Baire, Dawen Niu, Patrick H. Willoughby, Brian P. Woods and Thomas R. Hoye, Synthesis of complex benzenoids via the intermediate generation of o-benzynes through the hexadehydro-Diels-Alder reaction. Nat. Protoc., 2013, 8, 501.

  4. Thomas R Hoye, Beeraiah Baire, and Tao Wang. Tactics for probing aryne reactivity: mechanistic studies of silicon-oxygen bond cleavage during the trapping of (HDDA-generated) benzynes by silyl ethers. Chemical Science, 2014, 5, 545.

  5. Junhua Chen, Beeraiah Baire, and Thomas R. Hoye, Cycloaddition reactions of azide, furan, and pyrrole units with benzynes generated by the hexadehydro Diels-Alder (HDDA) reaction, Heterocycles, 2013, 88, 1191.

  6. Christian A. Hassig et al. Susan G. Brown, Beeraiah Baire, Thomas R Hoye, Andrew R. Michel etc., Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins. Journal of biomolecular screening, 2014, 19, 1201.

  7. A. Srikrishna, R. Ramesh Babu and B. Beeraiah, Enantiospecific synthesis of the ABC-ring system of A-nor and abeo 4(3-2) tetra and   pentacyclic triterpenes, Tetrahedron, 2010, 66, 852.

  8. A. Srikrishna, R. Ramesh Babu and B. Beeraiah, Enantiospecific synthesis of the tricyclic core structure of lippifolianes, Tetrahedron: Asymmetry, 2010, 21, 719.

  9. A. Srikrishna, B. Beeraiah and V. Gowri, Enantiospecific approach to the tricyclic core structure of tricyclo illicinone, ialibinones, and takaneones via ring-closing metathesis reaction, Tetrahedron, 2009, 65, 2649.

  10. A. Srikrishna and B. Beeraiah, Enantioselective syntheses of cis, syn, cis- and cis, anti, cis-linear triquinanes, Tetrahedron: Asymmetry, 2008, 19, 884.

  11. A. Srikrishna, B. Beeraiah and R. Ramesh Babu, Enantioselective total synthesis of (+)-laurokamurene B, Tetrahedron: Asymmetry, 2008, 19, 624.

  12. A. Srikrishna and B. Beeraiah, Enantiospecific synthesis of the complete carbon framework of the diterpenes komarovispiranes, Indian J. Chem., 2007, 46B, 1999.

  13. A. Srikrishna and B. Beeraiah, An enantiospecific synthesis of a komarovispirane, Tetrahedron: Asymmetry, 2007, 18, 2587.

  14. A. Srikrishna and B. Beeraiah, Synthesis of (±)-ar-macrocarpene, Synth. Commun., 2007, 37, 2855.

  15. A. Srikrishna and B. Beeraiah, Synthetic approaches to komarovispiranes. Enantiospecific synthesis of bicyclo[3.3.0]octanespiro[3.1']cyclohexanes, Tetrahedron Lett., 2007, 48, 2291.

  16. A. Srikrishna, B. Beeraiah and G. Satyanarayana, Chiral synthons from a-pinene: Enantioselective syntheses of bicyclo[3.3.0] and [3.2.1]octanones, Tetrahedron: Asymmetry, 2006, 17, 1544.

  17. A. Srikrishna and B. Beeraiah , First synthesis of (±) – tenuifolene and ar – tenuifolene, Indian J. Chem., 2005 44B, 1641.

  1. Cyclization methods. Thomas R Hoye, Beeraiah Baire, Dawen Niu, Patrick H Willoughby and Brian P Woods. US Patent App. 13/756,069.

  1. Formal Total Synthesis of Selaginpulvilin D. Bhavani Shankar Chinta and Beeraiah Baire*, Org. Biomol. Chem., 2017, 15, 5908-5911link

    BS OBC

    A Cover Page graphic has also been accepted for this paper.

    BS-OBC Cover Page Graphic

  2. The Z-enoate assisted, Meyer–Schuster rearrangement cascade: unconventional synthesis of α-arylenone esters Prabhakararao Tharra and Beeraiah Baire, Chem. Commun., 2016, 52, 12147-12150, was highlighted by inside back coverlink

    for website.giff

  3. Mild Approach to 2-acylfurans via Intercepted Meyer-Schuster rearrangement of 6-hydroxyhex-2-en-4-ynals. Prabhakara rao Tharra and Beeraiah Baire, J. Org. Chem., 2015, 80 (16), 8314–8328. was highlighted in Organic Chemistry Highlights June 2016link

  1. HDDA_Figure_1_-_Simple

    Hexadydro Diels-Alder (HDDA) Reaction Highlights

    1. Single molecules put a ring on it. Sarah E. Riesman, News and Views, Nature, 2012, 490, 179.

    2. Renewed focus on a neglected reaction. Chemical & Engineering News, 90 (42), October 15, 2012

    3. “A Hot,   Energized” Benzyne. Reinhard W. Hoffmann and Keisuke Suzuki, Angewandte Chemie International Edition Highlights, 2013, 52, 2655.

    4. The Hexadehydro-Diels-Alder Reaction-A New Method Yielding Benzenoids. Synfacts, 2013, 9(2), 0153.

    5. Drei mal drei, Michael Groß, Chem. Unserer Zeit, 2012, 46.

    6. Turbo-charged Diels-Alder reaction. Ian Le Guillou, Chemistry World.

    7. A new Diels-Alder reaction, Derek Lowe, Pipeline.

    8. The Hexadehydro-Diels-Alder Reaction: A New Chapter in Aryne Chemistry. Catherine Holden and Prof. Michael F. Greaney, Angewandte Chemie International Edition Highlights, 2014, 53, 5746.

    9. https://en.wikipedia.org/wiki/ Hexadehydro Diels-Alder_reaction