Additions to C-X bonds
Organometallic reagents of Al, Cu, Ti, Zr, C, Zn, Cd, Hg and Ce metals. Nucelophilic addition to imines, imine derivatives and carboxylic acid derivates; Carbanions stabilized by N,B, S, Si and Se, containing groups; epoxidation and skeletal reorganization; allyl organometallics, transition metal enolates, homoeneolates, metalloenamines, enol ethers, asymmetric synthesis with enol ethers; Eschenmoser coupling reactions; Passserini and Ugi reaction.
Carbon-carbon o-bond formation
Alkylation of enols,enolates; stabilized and non-stabilized carbanions; cyclization reactions; coupling reactions and rearrangements. Additions to and substitutiion at C-C ? bonds Organocuprates and conjugate reactins; nucleophiles with cationic pentadienyl- metal complexes; kroganopalladium reagents; carbometallation.
Combining C-C ? bonds
Ene reactions; oxa-di-?-metals photoisomerisation, transition metal mediated cycloadditions; retrogade Diels-Alder reactions; Nazarov cationic cylization; charge-transfer accelerated cyclization.
Synthesis of glycosides, sulphides, sulphoxides, phosphonium ylides and related compounds, Ritter type eaction; protecting groups; Nef reaction; reductive elimination; vicinal deoxygenation and vicinal desilylation.
Oxidation by remote functionalisation, microbial methods; epoxidation and asymmetric epoxidation; glycol formation; electrochemical oxidation; oxidative rearrangements; solid-support oxidants and electron transfer reactions.
Reduction by metal hydrides; asymmetric hydrogenation; enzymatic reduction; hydro-zirconation, – boration, – aluminatin and – silylation reaction.
Transition metals in organic synthesis; Birch-Pearson, Dotz, Heck-Stille, Hegedus, Mcmurray, Noyori, Pauson-Khand, Sharpless, Tebbe-Grubbs and Vollhardt reactions; asymmetric synthesis; chiral auxiliaries; catalytic enantioselective reactions; chemzymes. Antibody catalysis; biological-chemical transformations. Structural elucidation and reaction dynamics by multi-dimensional NMR spectroscopy and crystal diffraction methods; novel separation methods.